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Cholesterol-recognition motifs in the N-terminal domain (NTD) region of the spike S glycoprotein from SARS-CoV-2. Sequences of the cholesterol-recognition motifs, A) CRAC and b) CARC, localized in the NTD region of SARS-CoV-2 spike protein. C) CARC and CARC motifs are colored in the NTD segment. The yellow and orange segments represent the CARC129–141 and CRAC141–150 motifs, respectively. D) Close-up view of the segments shown in C).
