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. 2022 Dec 12;16(1):143–153. doi: 10.1016/j.jiph.2022.12.008

Table 4.

Influence of sociodemographic variables, lifestyle, vaccination status, pandemic wave and chronic diseases on the persistence of symptoms up to 4 weeks after the onset of COVID-19 and the number of symptoms.

Variable At least one symptom 4 weeks
after COVID-19#
The number of symptoms 4 weeks after COVID-19*
OR -95% CI + 95% CI p Value SD t p
Full model
COVID-19 severity 1.993 1.323 3.003 < 0.001 1.490 0.641 2.236 0.022
Age 0.967 0.929 1.001 0.643 -0.129 0.065 -1.999 0.049
Any sleep disorders 1.072 0.702 1.636 0.746 0.745 0.641 1.116 0.249
Smoking 1.809 0.803 4.075 0.153 -0.363 1.032 -0.352 0.726
Stress in the last
4 weeks before COVID-19
0.879 0.504 1.533 0.651 0.334 0.752 0.444 0.658
No regular activity
3 months before COVID
0.953 0.624 1.454 0.823 0.707 0.631 1.121 0.265
Sex, female 1.762 1.178 2.634 0.005 0.979 0.611 1.601 0.114
BMI 0.991 0.955 1.028 0.643 0.076 0.058 1.205 0.232
Diabetes Mellitus 0.974 0.601 1.573 0.914 0.897 0.827 1.085 0.282
Coronary Artery Disease 1.748 1.022 2.988 0.041 2.038 0.958 2.213 0.037
Heart Failure 0.922 0.299 2.848 0.889 -0.087 2.756 -0.032 0.974
Hypertension 0.897 0.585 1.368 0.614 0.194 0.708 0.273 0.785
COPD 0.856 0.390 1.882 0.700 5.443 2.043 2.665 0.009
Asthma 1.001 0.540 1.856 0.995 0.132 00.843 0.156 0.876
COVID-19 vaccination 1.398 0.636 3.071 0.403 0.001 0.609 0.003 0.998
III pandemic wave 1.048 0.662 0.715 0.841
IV pandemic wave 0.416 0.242 0.715 0.001
V pandemic wave 0.248 0.120 0.510 < 0.001
Reduced backward stepwise model
COVID-19 severity 1.816 1.118 2.783 0.006 1.733 0.563 3.075 0.002
Sex, female 1.747 1.189 2.567 0.004
IV pandemic wave 0.421 0.249 0.711 0.001
V pandemic wave 0.265 0.133 0.527 < 0.001
Coronary Artery Disease 1.836 0.880 2.087 0.039
COPD 4.571 1.884 2.425 0.017
Any sleep disorders 1.638 0.562 2.912 0.004

# – Linear regression analysis; * – Logistic regression analysis; OR – Odds ratio; COPD – chronic obstructive pulmonary disease; BMI – Body Mass Index. Statistically significant values are in bold with the significance level set at p < 0.05.