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Zelquistinel does not show sedative or ataxic side effects. At 5 minutes before the first test session, rats were dosed with ketamine (0.1, 1, or 10 mg/kg, IV), gabapentin (150 mg/kg, PO), or zelquistinel (10 mg/kg, PO). *P <.05 vs vehicle via a Tukey post hoc test (n = 6–12).
