Table 1.

Incidence rate and trend in non-cardia gastric cancer among US adults aged ≥20, 2000–2019.

	Case number No. %	Incidence rate, 2000 (95% CI)	Incidence rate, 2019 (95% CI)	Average APC, 2000-2009 (95% CI)	Average APC, 2010-2019 (95% CI)	Average APC, 2000–2019 (95% CI)
Overall	101,198	5.3 (5.1–5.4)	4.4 (4.3–4.5)	−1.0* (−1.1 to −0.9)	−1.0* (−1.1 to −0.9)	−1.0* (−1.1 to −0.9)
Sex
Men	55,256 (54.6)	7.0 (6.8–7.3)	5.1 (4.9–5.3)	−1.6* (−1.8 to −1.4)	−1.6* (−1.8 to −1.4)	−1.6* (−1.8 to −1.4)
Women	45,942 (45.4)	4.0 (3.9–4.2)	3.8 (3.7–4.0)	−0.4* (−0.6 to −0.2)	−0.4* (−0.6 to −0.2)	−0.4* (−0.6 to −0.2)
Age
20-64	37,301 (36.9)	1.9 (1.8–2.0)	2.2 (2.1–2.3)	0.8* (0.6 to 1.0)	0.8* (0.6 to 1.0)	0.8* (0.6 to 1.0)
≥65	63,897 (63.1)	21.2 (20.5–21.9)	14.6 (14.1–15.2)	−1.8* (−2.2 to −1.5)	−2.0* (−2.5 to −1.4)	−1.9* (−2.3 to −1.6)
Race/ethnicity#
Non-Hispanic white§	45,697 (45.2)	3.6 (3.5–3.8)	2.5 (2.4–2.6)	−2.2* (−2.6 to −1.7)	−1.4* (−1.8 to −1.1)	−1.8* (−2.1 to −1.5)
Non-Hispanic black	17,326 (17.1)	9.9 (9.2–10.7)	8.0 (7.5–8.5)	−1.5* (−1.8 to −1.1)	−1.5* (−1.8 to −1.1)	−1.5* (−1.8 to −1.1)
Hispanic	22,409 (22.1)	9.8 (9.1–10.6)	7.5 (7.1–7.9)	−1.4* (−1.7 to −1.2)	−1.4* (−1.7 to −1.2)	−1.4* (−1.7 to −1.2)
Non-Hispanic API	14,819 (14.6)	13.9 (12.8–15.1)	8.0 (7.5–8.6)	−2.8* (−3.2 to −2.5)	−2.8* (−3.2 to −2.5)	−2.8* (−3.2 to −2.5)
Geographic location
Metropolitan	92,142 (91.1)	5.5 (5.3–5.7)	4.6 (4.4–4.7)	−1.0* (−1.1 to −0.9)	−1.0* (−1.1 to −0.9)	−1.0* (−1.1 to −0.9)
Nonmetropolitan	8,852 (8.7)	3.9 (3.5–4.2)	2.9 (2.6–3.2)	−1.2* (−1.6 to −0.8)	−1.2* (−1.6 to −0.8)	−1.2* (−1.6 to −0.8)

APC, annual percentage change; API, Asian and Pacific Islander.

^*Indicates the average APC was significantly different from zero.

^#The stratified analysis by race/ethnicity was limited among Non-Hispanic White, Non-Hispanic Black, Hispanic and Non-Hispanic API.

^§Indicates that the average APCs of 2000–2009 and 2010–2019 was significantly different.