Fig. 3.
Comparison of clinical symptoms. The total number of eight clinical symptoms per COVID-19 wave of SD is shown A. In addition to analysis of variance, all COVID-19 waves were compared using the Tukey–Kramer method (fifth COVID-19 wave vs. first, second, third, and fourth COVID-19 waves: p < 0.0001). A comparison using analysis of variance for each of the eight clinical symptoms (disturbance of consciousness, p = 0.0291; fever, p < 0.0001; malaise, p < 0.0001; cough/sputum, p < 0.0001; dyspnea, p < 0.0001; nasal discharge/pharyngeal pain, p = 0.0256; gastrointestinal symptoms, abdominal pain/diarrhea/nausea and vomiting, p < 0.0001; and taste and smell disturbances, p < 0.0001) are shown in B