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. 2022 Dec 12;2022(12):CD013434. doi: 10.1002/14651858.CD013434.pub2

Comparison 2. Overall success of cannulation.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
2.1 Difficulty levels defined by original studies 12 1059 Risk Ratio (M‐H, Random, 95% CI) 1.27 [1.08, 1.49]
2.1.1 Difficult 10 670 Risk Ratio (M‐H, Random, 95% CI) 1.40 [1.10, 1.77]
2.1.2 No restriction by intravenous access difficulty level 2 389 Risk Ratio (M‐H, Random, 95% CI) 1.05 [0.92, 1.19]
2.2 Difficulty levels defined by the success rate with landmark method 12 1059 Risk Ratio (M‐H, Random, 95% CI) 1.27 [1.08, 1.49]
2.2.1 Difficult 8 588 Risk Ratio (M‐H, Random, 95% CI) 1.53 [1.12, 2.08]
2.2.2 Moderate 3 436 Risk Ratio (M‐H, Random, 95% CI) 1.07 [0.94, 1.23]
2.2.3 Easy 1 35 Risk Ratio (M‐H, Random, 95% CI) 1.00 [0.90, 1.11]
2.3 Operators could not see and palpate a target vein 4 294 Risk Ratio (M‐H, Random, 95% CI) 1.53 [0.98, 2.41]
2.4 Participants had a history of difficult intravenous access 6 390 Risk Ratio (M‐H, Random, 95% CI) 1.66 [0.97, 2.86]
2.5 Participants had multiple failed attempts 5 279 Risk Ratio (M‐H, Random, 95% CI) 1.53 [0.93, 2.51]
2.6 Operators finished any training program for ultrasound‐guided peripheral venous cannulation 10 670 Risk Ratio (M‐H, Random, 95% CI) 1.40 [1.10, 1.77]
2.6.1 Finished 9 610 Risk Ratio (M‐H, Random, 95% CI) 1.35 [1.06, 1.71]
2.6.2 Not specified 1 60 Risk Ratio (M‐H, Random, 95% CI) 1.91 [1.13, 3.23]
2.7 Operators had any clinical experience with ultrasound‐guided peripheral intravenous cannulation 10 670 Risk Ratio (M‐H, Random, 95% CI) 1.40 [1.10, 1.77]
2.7.1 Had any clinical experience 5 315 Risk Ratio (M‐H, Random, 95% CI) 1.15 [0.91, 1.44]
2.7.2 Did not have any clinical experience 3 235 Risk Ratio (M‐H, Random, 95% CI) 1.46 [1.18, 1.79]
2.7.3 Not specified 2 120 Risk Ratio (M‐H, Random, 95% CI) 2.08 [1.41, 3.09]
2.8 Operators finished any training program for ultrasound‐guided peripheral venous cannulation and had any clinical experience 10 670 Risk Ratio (M‐H, Random, 95% CI) 1.40 [1.10, 1.77]
2.8.1 Finished any training program for ultrasound‐guided peripheral venous cannulation and had any clinical experience 5 315 Risk Ratio (M‐H, Random, 95% CI) 1.15 [0.91, 1.44]
2.8.2 Not finished any training program for ultrasound‐guided peripheral venous cannulation or no clinical experience 3 235 Risk Ratio (M‐H, Random, 95% CI) 1.46 [1.18, 1.79]
2.8.3 Not specified 2 120 Risk Ratio (M‐H, Random, 95% CI) 2.08 [1.41, 3.09]
2.9 Types of operators 10 670 Risk Ratio (M‐H, Random, 95% CI) 1.40 [1.10, 1.77]
2.9.1 Nurses 8 551 Risk Ratio (M‐H, Random, 95% CI) 1.37 [1.05, 1.78]
2.9.2 Physicians 2 119 Risk Ratio (M‐H, Random, 95% CI) 1.72 [0.22, 13.47]
2.10 Setting 10 670 Risk Ratio (M‐H, Random, 95% CI) 1.40 [1.10, 1.77]
2.10.1 Emergency department 6 401 Risk Ratio (M‐H, Random, 95% CI) 1.57 [1.05, 2.36]
2.10.2 ICU 3 234 Risk Ratio (M‐H, Random, 95% CI) 1.36 [0.86, 2.15]
2.10.3 Operating room 1 35 Risk Ratio (M‐H, Random, 95% CI) 1.00 [0.90, 1.11]
2.11 Year of publication 10 670 Risk Ratio (M‐H, Random, 95% CI) 1.40 [1.10, 1.77]
2.11.1 Publication year: 1999 ~ 2008 2 95 Risk Ratio (M‐H, Random, 95% CI) 1.70 [0.10, 29.24]
2.11.2 Publication year: 2009 ~ 8 575 Risk Ratio (M‐H, Random, 95% CI) 1.36 [1.08, 1.71]
2.12 Dynamic guidance or static guidance 1 300 Risk Ratio (M‐H, Random, 95% CI) 1.10 [1.03, 1.18]
2.12.1 Dynamic 1 150 Risk Ratio (M‐H, Random, 95% CI) 1.10 [1.00, 1.21]
2.12.2 Static 1 150 Risk Ratio (M‐H, Random, 95% CI) 1.10 [1.00, 1.21]