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. 2022 Nov 28;12:962272. doi: 10.3389/fonc.2022.962272

Table 4.

Univariate and multivariate analyses of variables associated with GPC3-positive HCC.

Univariable Multivariable
OR (95%CI) P Value OR (95%CI) P Value
Tumor c (m/s) 0.484 (0.181, 0.816) *0.01 0.361 (0.158, 0.826) *0.02
Tumor φ (rad) 0.277 (0.036, 2.106) 0.22
Liver c (m/s) 0.903 (0.283, 2.882) 0.86
Liver φ (rad) 0.236 (0.019, 2.983) 0.26
Sex
 Male 1
 Female 0.362 (0.076, 1.719) 0.20
Age 0.982 (0.941, 1.025) 0.42
BMI 0.914 (0.787, 1.061) 0.24
Size 0.967 (0.820, 1.139) 0.69
Albumin (g/dL) 0.989 (0.889, 1.101) 0.84
Total bilirubin (umol/L) 1.062 (0.977, 1.155) 0.15
INR unit 0.516 (0.004, 64.255) 0.79
AFP (ng/mL) *0.001 8.117 (2.422, 27.199) *0.001
 <20 1
 ≥20 7.667 (2.384, 24.650)
CEA (ng/mL)
 <5 1
 ≥5 0.615 (0.105, 3.612) 0.59
CA125 (U/ml)
 <24 1
 ≥24 1.145 (0.334, 3.927) 0.83
CA199 (U/ml)
 <25 1
 ≥25 0.938 (0.334, 2.635) 0.90
Non-rim APHE
 Absent 1
 Present 2.296 (0.721, 7.315) 0.16
Nonperipheral washout
 Absent 1
 Present 0.588
(0.226, 1.533)
0.28
Enhancing capsule
 Absent 1
 Present 0.978
(0.376, 2.542)
0.96
LI-RADS
 Non-LR-5 1
 LR-5 1.214 (0.437, 3.374) 0.71

*P < 0.05.