Table 5.

Diagnostic performance of mechanical parameters c (stiffness) and serum marker AFP in detecting GPC3-positive HCC.

	Cutoff	AUC	P-value	Sensitivity (%)	Specificity (%)
c (m/sec)	2.8	0.674 [0.572-0.764]	…	84.2 (64/76) [74.0-91.6]	50.0 (12/24) [29.1-70.9]
AFP level (≥20mg/L)	20	0.719 [0.621-0.805]	0.57	60.5 (46/76) [48.6-71.6]	83.3 (20/24) [62.6-95.3]
c + AFP	…	0.803 [0.711-0.876]	*0.02	80.3 (61/76) [69.5-88.5]	70.8 (17/24) [48.9-87.4]

Unless otherwise specified, data in parentheses are numerators/denominators and data in brackets are 95% CIs. AUC of combined stiffness(c) and AFP level, denoted as c + AFP, was obtained by using probabilities estimated from logistic regression.