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. 2022 Dec 12;17(12):e0277188. doi: 10.1371/journal.pone.0277188

Fig 2.

Fig 2

(A) Collagen and ascorbic acid have beneficial effect on skin aging. (B) Fluorescence imaging of fibroblasts, keratinocytes, and melanocytes in the control and test groups at ×400 (Scale bar = 20 μm) and ×1000 (Scale bar = 5 μm) magnification. (C) fluorescence imaging of a cross-section of human skin tissue in the control and test groups (×400, Scale bar = 50 μm, n = 20). (D) Analysis of collagen synthesis depending on the concentration of the test product (n = 4, ***p < 0.001).