Skip to main content
. Author manuscript; available in PMC: 2023 Jun 2.
Published in final edited form as: Nat Metab. 2022 Jun 2;4(5):524–533. doi: 10.1038/s42255-022-00565-1

Extended Data Fig. 5 |. Dependency of DMi and 4-Oi on NRF2 and ATF3 for their anti-inflammatory effects in mouse BMDMs.

Extended Data Fig. 5 |

Cytokine secretion of BMDMs from wildtype (WT) and Nrf2-KO (a) or Atf3-KO (b) mice pre-treated with 0.25 mM DMI or 0.125 mM 4-OI for 4 h prior to LPS stimulation for 21 h. Data are shown as mean ± SEM calculated from n = 5 (a) or 3 (b) mice. P values were calculated by multiple unpaired t-test and overlayed on respective comparisons.