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. Author manuscript; available in PMC: 2022 Dec 12.
Published in final edited form as: Biochem Pharmacol. 2022 May 10;201:115080. doi: 10.1016/j.bcp.2022.115080

Table 2.

Frequently used MALDI matrixes to assist desorption and ionization of analyte.

Matrix Abbreviation Structures Applications References
2,6-Dihydroxyacetophenone DHA graphic file with name nihms-1849697-t0015.jpg lipids, proteins [77]
2,5-Dihydroxybenzoic acid DHB graphic file with name nihms-1849697-t0016.jpg small molecules, lipids, oligosaccharides [92,94]
1,5-Diaminonaphthalene DAN graphic file with name nihms-1849697-t0017.jpg lipids [158]
α-Cyano-4-hydroxycinnamic acid CHCA graphic file with name nihms-1849697-t0018.jpg small molecules, peptide, and proteins [159]
Sinapinic acid SA graphic file with name nihms-1849697-t0019.jpg peptide and proteins [77,159]