Date	Event	Description
12 December 2022	New search has been performed	Searches of the Cochrane Cystic Fibrosis and Genetic Disorders Group's Haemoglobinopathies Trials Register identified three potentially eligible references. One was an additional reference to an already included trial, but there was no additional information to be included in the review (Farber 1991). We discarded the remaining two references as one was not an RCT (Goldbaum 1979) and the second assessed the treatment for proliferative vitro retinopathy (Berman 1989). One trial (two references), previously listed in 'Studies awaiting classification', has now been included in the review (Sayag 2008).
12 December 2022	New citation required but conclusions have not changed	Two references representing one trial previously under awaiting classification in previous version was included in the review and the amendments were made accordingly (Sayag 2008). The conclusions of the review have not changed.