FIGURE 7.

Learning and memory performance for pigmented and albino mice, within both 5xFAD and WT mice at 6–9 months of age. (A–D) Learning performance (latency, distance, and cumulative search error) of albino and pigmented mice, within both WT and 5xFAD mice. Data are graphed and analyzed separately for males (A,B) and females (C,D). Performance is shown for both acquisition (A1‐3) and reversal training (R1‐3), separated by a dashed line. (E and F) Memory performance during the probe trial for male and female albino and pigmented mice as measured by percent time in each pool quadrant. Dashed line represents time in quadrants expected by chance (25%). (G) Swim‐speed during acquisition and reversal training, along with distance traveled during visible platform training for (G) male and (H) female pigmented and albino mice. ^, albinism difference, p < 0.05