Table 1.
Demographic data of liver patients and healthy controls (medians and interquartile ranges)
| Demographic data | Healthy Controls (CON; N = 21) | Acute Decompensation (AD; N = 20) | Acute-On-Chronic Liver Failure (ACLF; N = 10) |
|---|---|---|---|
| Age [years] | 53 (48–70) | 62 (51–68) | 56 (52–67) |
| Sex [male/female] | 10/12 | 14/6 | 7/3 |
| Child [A/B/C] | - | 1/15/4 | 1/1/8 |
| Aetiology of liver disease [OH/HCV/NASH/others] | - | 8/4/6/2 | 7/1/2/0 |
| MELD Score | - | 18 (14–24) | 26 (19–30) |
| Haemoglobin [g/dL] | 13.1 (12.3–14.0) | 9.6 (8.8–9.7) | 9.1 (7.3–10.0) |
| ACLF gradea [1/2/3] | - | - | 2/2/6 |
| Creatinine [mg/dL] | - | 1.1 (0.7–2.7) | 2.2 (1.0–4.2) |
| Na [mmol/L] | - | 136 (134–139) | 137 (134–140) |
| K [mmol/L] | - | 3.8 (3.5–4.1) | 4 (3.6–4.4) |
| Albumin [g/L] | - | 32 (23–33) | 24 (23–29) |
| Bilirubin [mg/dL] | - | 2.3 (1.5–3.4) | 9 (2–22) |
| PT [Quick; %] | 97(96–99) | 49 (46–58) | 37 (33–46) |
| APTT [sec] | 25(23–29) | 32 (29–35) | 39 (31–50) |
| Platelet count [nL−1] | 210(158–250) | 65 (55–101) | 46 (33–98) |
| Fibrinogen [g/L] | 3.3(3–3.9) | 2.3 (1.9–2.6) | 1.9 (1.4–2.9) |
aAt the time of blood sampling