Table I.

Baseline demographics of the pre-coronavirus 2019 (COVID-19) acute limb ischemia (ALI) cohort vs the COVID-19-associated ALI cohort

	Pre-COVID-19 ALI n = 74 (64.9%)	COVID-19 ALI n = 40 (35.1%)	P-value
Age, years	63.3 (14.4)	69.1 (11.4)	.029
Gender
Male	45 (61)	29 (72)	.23
Female	29 (39)	11 (28)
Ethnicity
White	65 (88)	36 (90)	.032
Black	7 (9)	0 (0)
Hispanic	0 (0)	1 (2)
Other/unknown	2 (3)	3 (8)
Smoking
Non-smoker	26 (35)	18 (46)	.38
Current smoker	19 (26)	6 (15)
Previous smoker	29 (39)	15 (38)
Intravenous drug use	4 (5)	0 (0)	.30
History of VTE	6 (8)	3 (8)	1.00
Hypertension	48 (65)	32 (80)	.13
CAD	28 (38)	13 (32)	.68
CHF	4 (5)	5 (12)	.27
Diabetes	25 (34)	16 (40)	.54
CKD	8 (11)	6 (15)	.56
ESRD	3 (4)	2 (5)	1.00
History of stroke/TIA	9 (12)	12 (30)	.024
HLD	29 (39)	14 (35)	.69
History of hypercoagulable disease	6 (8)	3 (8)	1.00
Malignancy	10 (14)	7 (18)	.59
COPD	15 (20)	11 (28)	.48
History of vascular intervention
None	44 (59)	29 (72)	<.001
Endoscopic	30 (41)	6 (15)
Open	0 (0)	5 (12)
History of amputation
None	65 (88)	35 (88)	.67
Minor amputation	6 (8)	2 (5)
Major amputation	3 (4)	3 (8)
Anticoagulation	17 (23)	8 (20)	.81
Aspirin	34 (46)	17 (42)	.84
Antiplatelets	26 (35)	8 (20)	.13
Rutherford classification
Class I	6 (8)	11 (28)	.025
Class IIa	30 (42)	13 (32)
Class IIb	34 (47)	13 (32)
Class III	2 (3)	3 (8)

CAD, Coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; ESRD, end-stage renal disease; HLD, hyperlipidemia; TIA, transient ischemic attack; VTE, venous thromboembolism.

Data are presented as number (%) or mean (standard deviation).