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Correlation of IL-12 and IFN-γ production by PBMC treated with Candida organismsa
| Treatment | Mean concn (pg/ml) ± SD (n = 6)
|
r2 | P | |
|---|---|---|---|---|
| IL-12 | IFN-γ | |||
| C. albicans SC5314 | ||||
| Live | <10 | <10 | ||
| Heat killed | 639 ± 158 | 1,281 ± 586 | 0.81 | <0.01 |
| C. krusei 6258 | ||||
| Live | 80 ± 32 | 459 ± 620 | 0.84 | <0.01 |
| Heat killed | 440 ± 106 | 1,201 ± 570 | 0.82 | <0.01 |
PBMC were treated with live or heat-killed C. albicans SC5314 and C. krusei 6258. Supernatants were collected after incubation for 20 h. Cytokines were measured by ELISA.
