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. 2022 Dec 12;42(12):BSR20221443. doi: 10.1042/BSR20221443

Figure 4. Leptin pretreatment increased GRP78 expression and decreased Caspase12 and CHOP levels after OGD/R.

Figure 4

(A) Cortical neurons costained for GRP78 (green), NeuN(red) and DAPI (blue) (scale: 10 μm). (B–E) The relative western blot images and analysis of GRP78, Caspase12 and CHOP in neurons in each group. The quantitative results are presented as the mean ± SEM (n = 3 per group). *P<0.05, versus the control group; **P<0.01, versus the control group; ***P<0.001, versus the control group; #P<0.05, versus the vehicle group; #P<0.05, versus the vehicle group; ###P<0.001, versus the vehicle group; P<0.05, versus the leptin group; ▲▲P<0.01, versus the leptin group; ▲▲▲P<0.001, versus the leptin group.