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. 2022 Nov 29;13:1072271. doi: 10.3389/fendo.2022.1072271

Table 2.

Sex steroid priming regimens for girls.

Dose Route of administration Timing prior to GHST
β-oestradiol (oestradiol valerate) 1 mg < 20 kg daily (bedtime)
2 mg >20 kg (55, 56, 68)
Oral For 2 (58) – 3 (55, 56) days
Ethinyloestradiol 10 or 20 or 30 or 50 mcg (69)
50 mcg twice a day (13)
100 mcg (58, 70)
20 mcg/m2 daily (bedtime) (61)
40 mcg/m2 daily (8)
50 mcg patch (62)
Oral
Oral
Oral
Oral
Oral
Oral
Transdermal
For 2 or 3 or 5 or 7 days
For 5 days
For 3 days
For 1-2 days
For 2 days
For 2 days
1 patch to be kept on for 3 days
Stilboestrol 5 mg twice a day (63)
1 mg twice a day (58, 64)
Oral
Oral
For 3 days
For 2 days
Premarin® (Conjugated oestrogen) 1.25 daily (47, 65)
2.5 mg (66)
Oral
Oral
For 3 days
1 dose the evening before and 1 dose the morning of the GHST