Table 2.
Sex steroid priming regimens for girls.
Dose | Route of administration | Timing prior to GHST | |
---|---|---|---|
β-oestradiol (oestradiol valerate) | 1 mg < 20 kg daily (bedtime) 2 mg >20 kg (55, 56, 68) |
Oral | For 2 (58) – 3 (55, 56) days |
Ethinyloestradiol | 10 or 20 or 30 or 50 mcg (69) 50 mcg twice a day (13) 100 mcg (58, 70) 20 mcg/m2 daily (bedtime) (61) 40 mcg/m2 daily (8) 50 mcg patch (62) |
Oral Oral Oral Oral Oral Oral Transdermal |
For 2 or 3 or 5 or 7 days For 5 days For 3 days For 1-2 days For 2 days For 2 days 1 patch to be kept on for 3 days |
Stilboestrol | 5 mg twice a day (63) 1 mg twice a day (58, 64) |
Oral Oral |
For 3 days For 2 days |
Premarin® (Conjugated oestrogen) | 1.25 daily (47, 65) 2.5 mg (66) |
Oral Oral |
For 3 days 1 dose the evening before and 1 dose the morning of the GHST |