TABLE 2.
Distribution of blood parameters in patients stratified according to their World Health Organization (WHO) score at baseline.
| WHO score ≤5 (n = 68; 75.6%) | WHO score >5 (n = 22; 24.4%) | P-value | |
| Hb g/dL | 12.7 + −2.1 (7.7–18.1) | 12.6 + −2.5 (7.6–16.1) | 0,839 |
| WBC (cells/μl) | 6,565 (4,660; 9212.5) (2,380–17,090) | 7,765(5682.5; 10147.5) (4210–21,150) | 0,131 |
| Neutrophils (N/mmc) | 5,525 (3,545; 7,735) (1,000–13,600) | 6,200 (4,385; 8007.5) (3,680–19,200) | 0,064 |
| Lymphocytes (N/mmc) | 845 (602.5; 1267.5) (260–2,970) | 635 (465; 1037.5) (270–3,350) | 0,069 |
| Platelets (cell/μL) | 225,000 (185,500; 282,000) (55,000–363,000) | 234,000 (134,750; 295,250) (31,000–607,000) | 0,974 |
| Fibrinogen (mg/dl) | 581.7 + −173.2 (283–1,000) | 563.2 + −187.2 (260–1,000) | 0,685 |
| INR | 1.1 (1.04; 1.22) (0.8–3.84) | 1.1 (1.03; 1.19) (0.8–1.33) | 0,622 |
| D-Dimer (mg/l) | 1.02 (0.56; 1.69) (0.04–18.99) | 0.94 (0.43; 2.38) (0.18–25.56) | 0,794 |
| Albumin (g/dl) | 3.5 + −0.5 (2.6–4.5) | 3.6 + −0.5 (2.5–5) | 0,562 |
| Total bilirubin mg/dl | 0.65 (0.45; 0.85) (0.21–5.09) | 0.74 (0.5; 1.06) (0.26–1.54) | 0,289 |
| Direct bilirubin mg/dl | 0.29 + −0.13 (0.1–0.76) | 0.34 + −0.17 (0.1–0.69) | 0,255 |
| Ferritin (ng/ml) | 533.5 (267.8; 744.5) (40–2,000) | 488 (149; 820) (39–2,000) | 0,816 |
| AST U/L | 25 (20; 33.5) (9–141) | 29 (23.5; 35.5) (8–176) | 0,135 |
| ALT U/L | 27 (19; 42) (7–177) | 35 (21.5; 55) (9–474) | 0,318 |
| LDH U/L | 289 (218; 383) (111–741) | 373 (281.8; 465) (193–670) | 0,013 |
| hsCRP mg/L | 9.3 (3.4; 33.8) (0.3–132.6) | 15.8 (9; 44.5) (1.3–222.5) | 0,039 |
| IL-6 (pg/ml) | 13.2 (7.2; 28.5) (2.3–63.4) | 19.6 (6.3; 59.9) (3.5–258) | 0,276 |
Data are expressed as mean ± standard deviation (range); median (25th; 75th percentile) (range) or absolute frequency (percentage). Hb, haemoglobin; WBC, white blood cells; INR, international normalized ratio; AST, aspartate transaminase; ALT, alanine transaminase; LDH, Lactate dehydrogenase; hsCRP, high sensitive C-reactive protein; IL-6, interleukin-6. Bold values indicate the strong correlation.