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. 2022 Dec 12;12:21437. doi: 10.1038/s41598-022-25934-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The mRNA expression levels of MCM6 and corresponding MCM6 proteomic profiles in control and SDS-exposed HaCaT cells. Histograms show (a) the fold change in MCM6 expression in SDS-exposed cells compared to control cells; (b) protein abundance of MCM6 assessed via LC–MS/MS analysis. The significant upregulations are marked with asterisks (*P = 3.8e−5; **P = 2.8e−5; ***P = 3.0e−4; at alpha level 0.05). Error bars represent the standard deviation between technical repeats.