TABLE 4.
Mutations located in rrl and rplD in six Mtb clinical strains and MICs of five oxazolidinones.
| ID | rrl | rplD | MIC (μ g/ml) | ||||
|
|
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| LZD | MRX-I | SZD | TZD | DZD | |||
| 15104 | C2060T | WT | 0.5 | 0.5 | ≤ 0.0625 | 0.25 | 2 |
| 6102 | C2572T | WT | 0.5 | 0.5 | ≤ 0.0625 | 0.125 | 2 |
| 22222 | C1275T | WT | ≤ 0.0625 | ≤ 0.0625 | ≤ 0.0625 | ≤ 0.0625 | 1 |
| 13204 | WT | G236A (Arg79His) | 0.5 | 0.5 | 0.25 | 0.25 | 2 |
| 11263 | WT | G236A (Arg79His) | 0.25 | 0.5 | ≤ 0.0625 | ≤ 0.0625 | 1 |
| 10181 | WT | G236A (Arg79His) | 0.25 | ≤ 0.0625 | ≤ 0.0625 | ≤ 0.0625 | 1 |