Skip to main content
. 2022 Nov 29;12:1061790. doi: 10.3389/fcimb.2022.1061790

Figure 2.

Figure 2

MiR-199a-3p over-expression exacerbated LPS-induced ARDS in mice. The agomir of MiR-199a-3p, agomir NC, antagomir of MiR-199a-3p, and antagomir NC were injected into mice via the tail vein. (A) MiR-199a-3p expression in lung tissue from mice in each group was detected by qRT-PCR (n=6 per group). (B) Histopathological images of lung samples (haematoxylin and eosin staining; scale bar = 200 µm). (C) Injury scores of the lung samples (n=6 per group). (D) Inflammatory cytokine levels in the lungs of mice from different groups were assessed using ELISA (n=6 per group). (E) Kaplan-Meier survival curves were used to demonstrate the effect of MiR-199a-3p on murine survival (n=7 per group). The experiments were repeated at least three times. Each value represents the mean ± SD of three independent experiments. *p < 0.05 vs. the agomir NC group, **p < 0.05 vs. the antagomir NC group, one-way ANOVA or log-rank test.