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. 2022 Nov 29;13:996248. doi: 10.3389/fphys.2022.996248

TABLE 1.

Common renal function and lipid indicators of the study subjects.

Group HC (n = 45) BKT (n = 40) RCC (n = 46) χ2/F, P
UA (μmol/L) 332.0 (269.3, 371.7) 282.4 (229.0, 350.8) 333.3 (236.4, 417.1) 4.354a, 0.113
C1q (mg/L) 207.0 (175.5, 235.5) 193.5 (168.4, 229.0) 191.5 (166.6, 221.8) 1.366a, 0.505
NGAL (μg/L) 95.0 (78.5, 113.0) 124.0 (85.3, 180.0) * 130.1 (93.0, 164.8) * 13.799a, 0.001
Urea (mmol/L) 5.10 (4.13, 5.64) 5.37 (4.07, 6.60) 5.43 (4.46, 6.59) 4.215a, 0.122
Cr (μmol/L) 66.0 (53.4, 78.0) 65.6 (54.2, 87.6) 80.1 (61.7, 105.7) * 11.775a, 0.003
CysC (mg/L) 0.91 (0.79, 1.00) 0.92 (0.76, 1.18) 1.07 (0.90, 1.26) * 13.391a, 0.001
eGFR (ml/min/1.73m2) 88.59 ± 12.29 85.75 ± 24.14 73.09 ± 20.85 * 8.057b, 0.001
TC (mmol/L) 4.58 ± 0.59 4.89 ± 1.11 5.17 ± 1.37 * 3.297b, 0.040
TG (mmol/L) 0.98 (0.87, 1.19) 1.29 (0.99, 2.37) * 1.39 (0.98, 1.97) * 13.261a, 0.001
HDL-C (mmol/L) 1.38 (1.14, 1.55) 1.31 (1.17, 1.64) 1.22 (1.05, 1.45) 2.717a, 0.257
LDL-C (mmol/L) 2.60 (2.27, 2.96) 3.13 (2.26, 3.56) * 2.99 (2.32, 4.31) * 9.355a, 0.009
Apo-A1 (g/L) 1.55 ± 0.21 1.53 ± 0.31 1.48 ± 0.27 0.834b, 0.437
Apo-B (g/L) 0.81 ± 0.14 0.93 ± 0.24* 1.00 ± 0.30* 7.263b, 0.001

Note: n, case; a is the χ2 value; b is the value of F; HC, healthy control; BKT, benign kidney tumor; RCC, renal cell carcinoma; Cr, creatinine; UA, uric acid; CysC, cystatin C; C1q, complement C1q; NGAL, neutrophil gelatinase-associated lipocalin; eGFR, estimated glomerular filtration rate; TC, total cholesterol; TG, triglyceride; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; Apo-A1, apolipoprotein A1; Apo-B, apolipoprotein B. Compared with HC, group, *p < 0.05. Compared with BKT, group, p < 0.05.