Table 2.
Estimate | P value | Overall P value | Hazard ratio (95% CI) | ||
---|---|---|---|---|---|
Gender | Female | −0.22 | <0.0001 | <0.0001 | 0.81 [0.77, 0.84] |
Male | |||||
Race | Black or African American | −0.02 | 0.57 | 0.0377 | 0.98 [0.91, 1.05] |
Other | −0.14 | 0.05 | 0.87 [0.78, 0.97] | ||
White | |||||
Performance status | Ambulatory | 0.28 | <0.0001 | <0.0001 | 1.32 [1.26, 1.38] |
In bed < 50% of time | 0.62 | <0.0001 | 1.86 [1.71, 2.03] | ||
Fully active | |||||
Weight loss | Weight loss > 5% | 0.18 | <0.0001 | <0.0001 | 1.20 [1.14, 1.26] |
Weight loss ≤ 5% | |||||
Disease | Advanced | 0.77 | <0.0001 | <0.0001 | 2.16 [1.94, 2.42] |
Early | |||||
Histology | Small cell lung cancer | −0.02 | 0.80 | 0.1293 | 0.98 [0.87, 1.11] |
Adenocarcinoma | 0.016 | 0.66 | 1.02 [0.95, 1.09] | ||
Other NSCLC | 0.065 | 0.08 | 1.07 [0.99, 1.15] | ||
Squamous | |||||
Age | 60 < Age < 70 | 0.04 | 0.06 | <0.0001 | 1.05 [1.00, 1.10] |
Age ≥ 70 | 0.15 | <0.0001 | 1.17 [1.11, 1.23] | ||
Age ≤ 60 | |||||
BMI | BMI ≥ 28 | −0.16 | <0.0001 | <0.0001 | 0.85 [0.79, 0.92] |
25 ≤ BMI < 28 | −0.14 | 0.00 | 0.87 [0.80, 0.94] | ||
22 ≤ BMI < 25 | −0.10 | 0.01 | 0.90 [0.84, 0.98] | ||
20 ≤ BMI < 22 | −0.04 | 0.41 | 0.96 [0.88, 1.05] | ||
BMI < 20 |
Abbreviations: BMI, body mass index; CI, confidence interval.