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. 2022 Oct 20;13(6):2650–2660. doi: 10.1002/jcsm.13095

Table 2.

Multivariable piecewise cox proportional hazards model for lung cancer patient cohort

Estimate P value Overall P value Hazard ratio (95% CI)
Gender Female −0.22 <0.0001 <0.0001 0.81 [0.77, 0.84]
Male
Race Black or African American −0.02 0.57 0.0377 0.98 [0.91, 1.05]
Other −0.14 0.05 0.87 [0.78, 0.97]
White
Performance status Ambulatory 0.28 <0.0001 <0.0001 1.32 [1.26, 1.38]
In bed < 50% of time 0.62 <0.0001 1.86 [1.71, 2.03]
Fully active
Weight loss Weight loss > 5% 0.18 <0.0001 <0.0001 1.20 [1.14, 1.26]
Weight loss ≤ 5%
Disease Advanced 0.77 <0.0001 <0.0001 2.16 [1.94, 2.42]
Early
Histology Small cell lung cancer −0.02 0.80 0.1293 0.98 [0.87, 1.11]
Adenocarcinoma 0.016 0.66 1.02 [0.95, 1.09]
Other NSCLC 0.065 0.08 1.07 [0.99, 1.15]
Squamous
Age 60 < Age < 70 0.04 0.06 <0.0001 1.05 [1.00, 1.10]
Age ≥ 70 0.15 <0.0001 1.17 [1.11, 1.23]
Age ≤ 60
BMI BMI ≥ 28 −0.16 <0.0001 <0.0001 0.85 [0.79, 0.92]
25 ≤ BMI < 28 −0.14 0.00 0.87 [0.80, 0.94]
22 ≤ BMI < 25 −0.10 0.01 0.90 [0.84, 0.98]
20 ≤ BMI < 22 −0.04 0.41 0.96 [0.88, 1.05]
BMI < 20

Abbreviations: BMI, body mass index; CI, confidence interval.