Table 2.
Sensitivity and specificity of a T2H2O threshold in predicting decline in North Star Ambulatory Assessment for Dysferlinopathy (NSAD) score
| Muscle | Threshold | Analysis | Decline of >1 point on NSAD in 1 year | Decline of >5 points on NSAD in 3 years |
|---|---|---|---|---|
| Adductor magnus | 39.0 ms | Sensitivity | 57% | 63% |
| Specificity | 71% | 78% | ||
| Vastus intermedius | 39.4 ms | Sensitivity | 86% | 100% |
| Specificity | 57% | 67% | ||
| Vastus lateralis | 40.5 ms | Sensitivity | 71% | 88% |
| Specificity | 71% | 78% | ||
| Vastus medialis | 40.1 ms | Sensitivity | 86% | 88% |
| Specificity | 57% | 67% | ||
| Muscle grouping | ||||
| All four muscles over threshold bilaterally | Respective threshold for each muscle as above | Sensitivity | 43% | 63% |
| Specificity | 71% | 89% | ||
| At least one muscle over threshold bilaterally | Sensitivity | 86% | 100% | |
| Specificity | 57% | 56% | ||