Table 1. Demographic and clinical characteristics of patients who underwent resection of suspicious GGO nodules, stratified by benign versus malignant etiologies.
| Characteristics | Adenocarcinoma (N=208) | Benign pathology (N=35) | P value |
|---|---|---|---|
| Age (years), mean ± SD | 67.37±10.04 | 59.86±13.30 | <0.001* |
| Sex, n (%) | 0.106 | ||
| Male | 66 (31.7) | 16 (45.7) | |
| Female | 142 (68.3) | 19 (54.3) | |
| Race/Ethnicity, n (%) | 0.009* | ||
| Non-Asian | 139 (66.8) | 31 (88.6) | |
| Asian | 69 (33.2) | 4 (11.4) | |
| Smoking history, n (%) | 116 (55.8) | 20 (57.1) | 0.880 |
| Average smoking pack years, mean ± SD | 27.14±21.71 | 24.55±18.49 | 0.617 |
| Patients with no comorbidities, n (%) | 86 (41.3) | 14 (40.0) | 0.881 |
| Radiologic characteristics | |||
| Average total size of GGO, mean ± SD | 2.62±1.71 | 1.35±0.99 | <0.001* |
| Pure GGO (100%) nodules | 21 (10.1%) | 0 | 0.05 |
| Percent solid, mean ± SD | 59.6±32.9 | 65.7±36.1 | 0.32 |
| PET scan results, n (%) | 0.09 | ||
| Not done | 34 (16.3) | 10 (28.6) | |
| Non-avid | 20 (9.6) | 8 (22.9) | |
| Mild activity (0.1–2.5 SUV) | 61 (29.3) | 5 (14.3) | |
| Hypermetabolic (>2.5 SUV) | 93 (44.7) | 12 (34.3) |
*, statistically significant P value. GGO, ground glass opacity; SD, standard deviation; PET, positron emission tomography; SUV, maximum standardized uptake value.