Table 13.

Recommendations and Levels of Evidence for Drug Therapy in Patients With PVCs

	COR	LOE	GOR (MINDS)	LOE (MINDS)
Use of β‐blockers and calcium antagonists to improve QOL in patients with symptomatic PVCs without organic heart disease ⁷³ , ⁷⁴	IIa	B	B	II
Use of β‐blockers and amiodarone to improve symptoms and left ventricular function in patients with cardiomyopathy secondary to frequent PVCs ⁷⁹ , ⁸⁰ , ⁸¹	IIa	B	B	III
Use of classes IA and IC antiarrhythmic drugs to patients with PVCs following myocardial infarction ³³	III	B	D	II

Abbreviations: Ca, calcium; COR, class of recommendation; GOR, grade of recommendation; LOE, level of evidence; MINDS, Medical Information Network Distribution Service; PVC, premature ventricular contraction; QOL, quality of life.