Table 32.

Hazard Ratios for Ischemic Stroke in Japanese Patients With AF

Factors	HR (95% CI)
Age
<65 years65–74 years≥75 years	Reference1.12 (0.53–2.37)2.31 (1.18–4.52)
Women	1.07 (0.65–1.76)
Hypertension	1.69 (1.01–2.86)
Diabetes mellitus	1.18 (0.64–2.15)
Cerebral infarction or TIA	3.25 (1.86–5.67)
Heart failure	0.86 (0.45–1.65)
Coronary artery disease	0.52 (0.22–1.26)
Antiplatelet use	1.42 (0.86–2.32)

Multivariate Cox regression model. Pooled analysis of the Shinken Database, J‐RHYTHM Registry, and Fushimi AF Registry in patients with AF not receiving anticoagulation therapy (n=3,588).

Abbreviation: AF, atrial fibrillation; CI, confidence interval; HR, hazard ratio; TIA, transient ischemic attack.

(Adapted from Suzuki S, et al. 2015. ²⁴⁹ )