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. 2022 Oct 25;38(6):833–973. doi: 10.1002/joa3.12714

Table 69.

Recommendations and Levels of Evidence for Injection at the Time of CPR for VF/pVT

COR LOE GOR (MINDS) LOE (MINDS)
nifekalant administration to obtain ROSC for VF/pVT with no response to CPR 740 , 741 , 742 , 883 , 884 , 885 , 886 , 887 , 888 , 889 , 890 , 891 IIa B B I
amiodarone administration to obtain ROSC for VF/pVT with no response to CPR 739 , 740 , 741 , 743 , 883 , 884 , 885 , 892 , 893 , 894 , 895 IIa A B I
magnesium administration for polymorphic VT associated with QT prolongation 901 IIa B B III
Sympathetic block treatment for ES and antiarrhythmic drug‐resistant VF/pVT 753 , 754 , 783 , 896 , 899 IIa C B III
lidocaine administration to obtain ROSC for VF/pVT with no response to CPR 739 , 740 , 743 , 883 IIb B C2 I
Prophylactic routine administration of lidocaine for VF/pVT after ROSC 900 IIb B C1 IVa
Routine administration of β‐blocker (p.o./i.v. injection) in early stage after ROSC 901 IIb C C1 IVb
Routine administration of magnesium for adult VF/pVT 879 , 880 III A D I
Routine administration of atropine for PEA and asystole 881 , 882 III B D IVa

Abbreviations: COR, class of recommendation; CPR, cardiopulmonary resuscitation; ES, electrical storm; GOR, grade of recommendation; ICD, implantable cardioverter‐defibrillator; LOE, level of evidence; MINDS, Medical Information Network Distribution Service; PEA, pulseless electrical activity; pVT, pulseless ventricular tachycardia; ROSC, return of spontaneous circulation; VF, ventricular fibrillation; VT, ventricular tachycardia.