Table 70.
Recommendations and Levels of Evidence for Prophylactic Therapeutic Intervention for Recurrent Tachyarrhythmias due to WPW Syndrome in Pediatric Patients
| COR | LOE | GOR (MINDS) | LOE (MINDS) | |
|---|---|---|---|---|
| Patients with aborted sudden cardiac death, syncope or decreased cardiac function, and body weight ≥15 kg | ||||
| Catheter ablation | I | C | C1 | V |
| Use of Class IC drugs (e.g., flecainide) | IIa | C | C1 | V |
| Use of β‐blockers | IIb | C | C2 | VI |
| Patients with recurrent persistent SVT induced on electrophysiology study, or palpitations, and body weight ≥15 kg | ||||
| Catheter ablation | I | C | C1 | V |
| Use of Class IC drugs | I | C | C1 | V |
| Use of sotalol | IIa | C | C1 | V |
| Use of amiodarone | IIb | C | C2 | VI |
| Patient with recurrent and/or symptomatic SVT, and body weight <15 kg | ||||
| Use of Class IC drugs | I | C | B | IVa |
| Use of sotalol, Class IA drugs (e.g., disopyramide) | IIa | C | C1 | V |
| Use of β‐blocker, amiodarone | IIb | C | C1 | V |
| Catheter ablation | IIb | C | C1 | V |
| Asymptomatic patient | ||||
| Arrhythmic drug therapy | III | C | D | V |
Abbreviations: COR, class of recommendation; GOR, grade of recommendation; LOE, level of evidence; MINDS, Medical Information Network Distribution Service; SVT, supraventricular tachycardia; WPW, Wolff‐Parkinson‐White.