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. 2022 Oct 25;38(6):833–973. doi: 10.1002/joa3.12714

Table 70.

Recommendations and Levels of Evidence for Prophylactic Therapeutic Intervention for Recurrent Tachyarrhythmias due to WPW Syndrome in Pediatric Patients

COR LOE GOR (MINDS) LOE (MINDS)
Patients with aborted sudden cardiac death, syncope or decreased cardiac function, and body weight ≥15 kg
Catheter ablation I C C1 V
Use of Class IC drugs (e.g., flecainide) IIa C C1 V
Use of β‐blockers IIb C C2 VI
Patients with recurrent persistent SVT induced on electrophysiology study, or palpitations, and body weight ≥15 kg
Catheter ablation I C C1 V
Use of Class IC drugs I C C1 V
Use of sotalol IIa C C1 V
Use of amiodarone IIb C C2 VI
Patient with recurrent and/or symptomatic SVT, and body weight <15 kg
Use of Class IC drugs I C B IVa
Use of sotalol, Class IA drugs (e.g., disopyramide) IIa C C1 V
Use of β‐blocker, amiodarone IIb C C1 V
Catheter ablation IIb C C1 V
Asymptomatic patient
Arrhythmic drug therapy III C D V

Abbreviations: COR, class of recommendation; GOR, grade of recommendation; LOE, level of evidence; MINDS, Medical Information Network Distribution Service; SVT, supraventricular tachycardia; WPW, Wolff‐Parkinson‐White.