TABLE 2.
Participants' characteristics for each legacy cohorts
| Cohort | N | Age | Sex (F) | Education | Hypertension (Y) | Diabetes (Y) | Smoking Status (Y) | mFW | EFC |
|---|---|---|---|---|---|---|---|---|---|
| UCSF | 182 |
70.0 ± 10.8 [45.5; 91] |
96; 52.7 |
17.8 ± 2.8 [5;26] |
46; 25.3 | 8; 4.4 | 46; 25.3 |
0.23 ± 0.038 [0.11; 0.36] |
−1.09 ± 0.74 [−2.34; 0.44] |
| ADRC UCD | 173 |
76.1 ± 6.9 [65; 97] |
11; 63.6 |
14.9 ± 3.9 [0; 20] |
105; 60.7 | 51; 29.5 | Not Available |
0.22 ± 0.05 [0.14; 0.58] |
−0.66 ± 0.79 [−2.62; 1.15] |
| RUSH | 302 |
77.5 ± 6.5 [62.1; 97.8] |
249; 82.5 |
16.0 ± 3.7 [5; 30] |
205; 68.1 | 73; 25.3 | 123; 40.7 |
0.24 ± 0.037 [0.15; 0.37] |
−0.41.3 ± 0.72 [−2.43; 1.55] |
| ARIC | 1837 |
76.3 ± 5.3 [67.5; 90] |
1105; 60.15 |
15.3 ± 4.2 [1; 21] |
1370; 75.2 | 600; 33.1 | 97; 5.5 |
0.27 ± 0.062 [0.17; 0.70] |
−0.94.3 ± 0.74 [−2.71; 1.42] |
| FHS | 2902 |
55 ± 14 [25; 92] |
1569; 54.1 |
15.1 ± 3.3 [4; 22] |
932; 32.1 | 212; 7.3 | 213; 7.3 |
0.19 ± 0.034 [0.12; 0.38] |
−0.23 ± 0.74 [−2.76; 2.09] |
| Offspring | 889 |
71 ± 8 [48; 92] |
501; 54.1 | 506; 56.9 | 118; 13.3 | 40; 4.5 | 0.23 ± 0.04 [0.15; 0.38] |
−0.58 ± 0.73 [−2.63; 1.36] |
|
| Gen3 | 1937 |
48 ± 9 [ 25; 85] |
1068; 55.1 | 418; 21.6 | 92; 4.8 | 166; 8.6 | 0.18 ± 0.02 [0.12; 0.30] |
−0.07 ± 0.69 [−2.76; 2.09] |
Note: Continuous variable: mean ± SD [min; max]; categorical variable: N; %.
Abbreviations: EFC, executive function composite score; mFW, mean free water.