Table 5.

T Lymphocyte and Natural Killer Cell Changes in Plasma From 5 Patients Treated With IVCY

…	Patient No.	Pretreatment	Treatment Duration, mo						Post-treatment Duration, mo
			1	2	3	4	5	6	3	6	9	12	18	24
CD3+ T lymphocyte count, /μL	1	1522	1387	729	1231	1029	821	924	1084	1478	1297	1136	1191	1204
	2	955	1829	777	671	891	811	932	1543	1021	1231	1443	1321	1211
	3	2845	3578	2467	2571	1941	1625	1731	2455	1625	2935	2030	2725	2111
	4	1941	834	582	1668	1044	917	953	1156	1234	1275	917	953	538
	5	1432	1321	1516	1093	1102	783	982	1201	1124	1342	994	1432	876
CD4+ T lymphocyte count, /μL	1	676	538	354	510	478	342	453*	493	623	525	389	498	501
	2	597	900	259	321	231	342	432	558	689	652	590	602	634
	3	1268	1562	1197	1297	942	689	673	1043	689	1339	860	1558	1101
	4	1127	434	235	803	717	487	486	706	655	675	487	486	273
	5	873	653	768	621	542	412	491	665	662	764	543	698	478
CD4+ T lymphocyte cell, %	1	34	28	38	31	36	30	39	35	32	30	24	31	31
	2	47	39	23	37	15	31	36	26	38	35	30	35	38
	3	35	33	38	40	32	29	28	32	32	35	32	39	42
	4	42	42	30	38	41	32	34	41	38	38	41	40	37
	5	46	39	40	37	39	35	36	35	40	36	37	38	44
CD8+ T lymphocyte count, /μL	1	824	776	361	686	532	381	443	621	843	754	717	672	602
	2	332	859	393	220	473	384	453	459	432	444	465	421	390
	3	1463	1858	1172	1169	934	889	832	1311	889	1514	1124	1100	892
	4	744	348	287	735	360	415	348	402	492	524	360	415	231
	5	463	563	717	401	390	221	432	402	394	453	387	664	256
CD8+ T lymphocyte cell, %	1	34	34	39	45	38	26	27	37	37	37	43	36	40
	2	24	36	29	22	23	27	28	19	22	22	22	21	22
	3	31	31	27	25	28	34	28	23	24	21	25	20	22
	4	28	32	29	24	24	25	26	24	29	31	29	23	22
	5	22	32	27	26	25	18	33	23	25	23	28	26	19
Natural killer cell, %	1	14.64	34.96	13.2	24.24	12.1	8.3	10.2	18.8	13.2	17.16	32.48	16.3	14.2
	2	15.35	13.44	9.8	17.73	13.3	11.54	13.86	8.9	30.07	22.01	9.1	7.3	15.6
	3	13.44	15.35	17.73	13.86	14.75	9.8	13.3	15.6	30.07	22.01	29.74	9.53	7.3
	4	4.23	9.78	25.72	14	7.8	15.3	12.9	18	16.03	12.3	38.1	11.8	9.3
	5	21.1	10.3	36.71	12.4	15.2	11.2	9.93	17.4	19.2	14.5	14.3	12.5	16.21
Natural killer cell, /μL	1	223	485	96	298	125	68	94	204	195	223	369	194	171
	2	147	246	76	119	119	94	129	137	307	271	131	96	189
	3	382	549	437	356	286	159	230	383	489	646	604	260	154
	4	82	82	150	2342	81	140	123	208	198	157	349	112	50
	5	302	136	557	136	168	88	98	209	216	195	142	179	142

Normal range: CD3⁺ T lymphocyte count: 690–254/μL; CD4⁺ T lymphocyte count: 410–1590/μL; CD4⁺ T lymphocyte cell: 30.1%–40.4%; CD8⁺ T lymphocyte count: 190–1140/μL; CD8⁺ T lymphocyte cell: 20.7%–29.4%; natural killer cell: 9%–15%.

Abbreviation: IVCY, intravenous cyclophosphamide.

*The 6-month CD4⁺ T lymphocyte count compared with pretreatment (*P < .05)