Table 6.

B Cell and Serum Immunoglobulin Changes in 5 Patients With IVCY

…	Patient No.	Pretreatment	Treatment Duration, mo						Post-treatment Duration, mo
			1	2	3	4	5	6	3	6	9	12	18	24
CD19+ B cell, %	1	7.08	7.62	8.9	12	5.2	7.4	6.4	12.07	12.3	10.92	9.08	10.8	13.1
	2	10.2	7.2	9.2	8.1	7.3	6.9	9.1	9.9	10.9	8.9	11.9	10.9	12.1
	3	8.22	7.12	7.66	6.55	6.68	5.62	8.3	7.95	3.52	7.23	8.99	13.4	11.6
	4	21.86	15.92	9.65	7	10	8.1	6.5	10	4.99	11.2	17.5	10.7	9.89
	5	13.2	10.2	7.13	6.32	6.22	5.45	6.01	6.54	8.88	7.49	8.9	9.09	9.98
CD19+ B cell, /μL	1	108	106	65	148	54	61	59	131	182	142	103	129	158
	2	97	132	72	54	65	56	85	153	111	110	172	144	147
	3	234	255	189	168	130	91	144	195	57	212	183	365	245
	4	424	133	56	118	104	74	62	116	62	143	160	102	53
	5	189	135	108	69	69	43	59	79	100	101	88	130	87
IgG, g/L	1	19.2	19.9	20.47	25.97	23.85	24.05	18.21	24.05	25.26	26.53	35.81	23.85	24.04
	2	12.61	11.93	11.14	10.75	12.9	9.9	8.9	10.75	12.9	14.2	11.2	9.7	10.7
	3	12.1	12.45	12.65	13.13	10.97	12.45	9.45	9.45	10.57	10.58	12.02	43.43	37.02
	4	10.77	10.81	10.54	9.86	9.89	8.21	7.54	10.73	9.9	11.98	13.46	14.58	17.79
	5	15.79	16.12	14.17	15.52	13.39	14.22	13.7	15.3	15.92	16.34	15.98	14.38	15.34
IgA, g/L	1	1.47	1.55	1.58	1.86	1.76	1.52	1.43	1.53	1.84	2.25	2.64	2.11	1.98
	2	1.67	1.7	1.69	1.54	1.41	1.21	1.09	1.54	1.67	1.65	2.43	2.11	1.98
	3	1.62	1.54	1.59	1.63	1.57	1.58	1.45	1.45	1.38	1.21	1.56	2.11	1.86
	4	1.5	1.71	1.66	1.5	1.49	1.34	1.31	1.42	1.27	1.49	1.53	1.57	1.63
	5	2.3	2.11	2.34	2.53	2.1	2.04	1.93	1.98	2.11	2.53	2.31	2.22	2.32
IgM, g/L	1	1.21	1.3	1.14	1.02	0.93	0.96	0.89	1.09	1.34	1.66	1.42	1.23	1.19
	2	1.07	1.17	1.27	1.2	1.01	1.04	0.91	1.11	1.21	1.23	1.29	1.22	1.17
	3	1.77	1.76	1.76	1.8	1.65	1.81	1.48	1.55	1.71	1.71	1.9	1.65	1.27
	4	1.82	1.9	1.87	1.57	1.55	1.48	1.4	1.73	1.54	2.36	2.03	2.26	3.45
	5	1.52	1.56	1.46	1.43	1.29	1.54	1.62	1.47	1.57	1.55	1.34	1.45	1.62

Normal range: CD19⁺ B cell: 9.02%–14.1%; IgG: 8–18.0 g/L; IgA: 2.01–2.69 g/L; IgM: 0.84–1.32 g/L.

Abbreviations: Ig, immunoglobulin; IVCY, intravenous cyclophosphamide.