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. 2022 Nov 29;8(12):2552–2563. doi: 10.1021/acsinfecdis.2c00445

Table 3. MICs of MGB-BP-3 and Relevant Control Antibiotics against the surA and tolC Mutants from the E. coli Keio Collection.

    MGB-BP-3 (μM)
    MIC CIP MIC (μg/mL) RIF MIC (μg/mL)
JW0052 surA knockout (membrane) >100 0.02 8
JW5503 tolC knockout (efflux) 0.39 0.004 2
BW25113 WT 6.25 0.02 4