Table 3. MICs of MGB-BP-3 and Relevant Control Antibiotics against the surA and tolC Mutants from the E. coli Keio Collection.
MGB-BP-3 (μM) |
||||
---|---|---|---|---|
MIC | CIP MIC (μg/mL) | RIF MIC (μg/mL) | ||
JW0052 | surA knockout (membrane) | >100 | 0.02 | 8 |
JW5503 | tolC knockout (efflux) | 0.39 | 0.004 | 2 |
BW25113 | WT | 6.25 | 0.02 | 4 |