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N-Phenyl-1-naphthyl (NPN) uptake in E. coli upon incubation with PmxB4/ent-PmxB4 and PMBN/ent-PMBN. (A, B) NPN uptake in polymyxin-sensitive strains ATCC 25922 (smooth LPS) and BW25113 (rough LPS); (C) NPN uptake in the polymyxin-resistant, mcr-1 positive strain. Values and associated error bars are based on triplicates with fluorescence read-out after 1 h of incubation. RFU: relative fluorescence unit.
