Table 1. Minimal Inhibitory Concentration (MIC) Values for PmxB4 and ent-PmxB4a.
| strain | PmxB4 | ent-PmxB4 | PmxB (commercial) | |
|---|---|---|---|---|
| E. coli | ATCC 25922 | 0.25 | 128 | 1 |
| BW25113 | 0.5 | >128 | 1 | |
| mcr-1 | 4 | 128 | 4 | |
| JW3594 (ΔwaaD) | 0.06 | 128 | 0.06 | |
| JW3596 (ΔwaaC) | 0.06 | 128 | 0.06 | |
| K. pneumoniae | ATCC 13883 | 0.125 | >128 | 0.25 |
| A. baumannii | ATCC 19606 | 0.5 | >128 | 0.25 |
| P. aeruginosa | ATCC 27853 | 0.25 | >128 | 1 |
| NRZ03961 | 0.25 | >128 | 1 | |
| ATCC 10145 | 0.25 | >128 | 1 | |
| 2018-007 | 0.5 | >128 | 2 |
a
MIC values are derived from triplicate experiments and are expressed as μg/mL. See Figure S7 for the analysis of PmxB obtained from commercial sources.