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. 2022 Dec 5;10:e14481. doi: 10.7717/peerj.14481

Table 2. Univariate and multivariate analysis of factors that contribute to clinical remission in IgA nephropathy.

Variable Univariate Analysis Multivariate Analysis
HR 95% CI P-value HR 95% CI P-value
Age (per decade) 1.02 (0.84–1.22) 0.872 1.11 (0.90–1.37) 0.337
Gender (male vs female) 0.80 (0.59–1.09) 0.158 0.71 (0.48–1.05) 0.088
Hematuria (vs no hematuria) 0.53 (0.36–0.80) 0.003* 0.59 (0.38–0.90) 0.015*
Proteinuria (g/24h) 0.71 (0.57–0.89) 0.003* 0.74 (0.57–0.95) 0.017*
Serum creatinine (per 10 µmoI/L) 0.96 (0.91–1.02) 0.145 0.98 (0.89–1.07) 0.585
Mean arterial pressure (per 10 mmHg) 0.98 (0.86–1.11) 0.743 1.06 (0.92–1.23) 0.426
M (M0 vs M1) 0.78 (0.58–1.06) 0.112 0.74 (0.54–1.03) 0.073
E (E0 vs E1) 0.47 (0.07–3.33) 0.446 0.60 (0.08–4.73) 0.630
S (S0 vs S1) 1.32 (0.90–1.94) 0.152 1.51 (0.99–2.28) 0.053
T (T0 vs T1+T2) 0.49 (0.32–0.75) 0.001* 0.50 (0.31–0.81) 0.005*
C (C0 vs C1+C2) 1.04 (0.75–1.45) 0.797 1.27 (0.89–1.83) 0.188
Tonsillectomy 1.75 (1.28–2.39) <0.001* 1.77 (1.29–2.42) <0.001*
Steroid/Immunosuppressant 0.91 (0.67–1.24) 0.550 1.00 (0.72–1.39) 0.990
RAS inhibitor 0.99 (0.71–1.40) 0.965 0.99 (0.68–1.44) 0.974

Notes.

HR
hazard ratio
CI
confidence interval
*

Statistically significant.