Table 2. Univariate and multivariate analysis of factors that contribute to clinical remission in IgA nephropathy.
| Variable | Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Age (per decade) | 1.02 | (0.84–1.22) | 0.872 | 1.11 | (0.90–1.37) | 0.337 |
| Gender (male vs female) | 0.80 | (0.59–1.09) | 0.158 | 0.71 | (0.48–1.05) | 0.088 |
| Hematuria (vs no hematuria) | 0.53 | (0.36–0.80) | 0.003* | 0.59 | (0.38–0.90) | 0.015* |
| Proteinuria (g/24h) | 0.71 | (0.57–0.89) | 0.003* | 0.74 | (0.57–0.95) | 0.017* |
| Serum creatinine (per 10 µmoI/L) | 0.96 | (0.91–1.02) | 0.145 | 0.98 | (0.89–1.07) | 0.585 |
| Mean arterial pressure (per 10 mmHg) | 0.98 | (0.86–1.11) | 0.743 | 1.06 | (0.92–1.23) | 0.426 |
| M (M0 vs M1) | 0.78 | (0.58–1.06) | 0.112 | 0.74 | (0.54–1.03) | 0.073 |
| E (E0 vs E1) | 0.47 | (0.07–3.33) | 0.446 | 0.60 | (0.08–4.73) | 0.630 |
| S (S0 vs S1) | 1.32 | (0.90–1.94) | 0.152 | 1.51 | (0.99–2.28) | 0.053 |
| T (T0 vs T1+T2) | 0.49 | (0.32–0.75) | 0.001* | 0.50 | (0.31–0.81) | 0.005* |
| C (C0 vs C1+C2) | 1.04 | (0.75–1.45) | 0.797 | 1.27 | (0.89–1.83) | 0.188 |
| Tonsillectomy | 1.75 | (1.28–2.39) | <0.001* | 1.77 | (1.29–2.42) | <0.001* |
| Steroid/Immunosuppressant | 0.91 | (0.67–1.24) | 0.550 | 1.00 | (0.72–1.39) | 0.990 |
| RAS inhibitor | 0.99 | (0.71–1.40) | 0.965 | 0.99 | (0.68–1.44) | 0.974 |
Notes.
- HR
- hazard ratio
- CI
- confidence interval
Statistically significant.