Table 3. Univariate and multivariate analysis of factors that contribute to renal survival in IgA nephropathy.
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Age (per decade) | 1.12 | (0.68–1.84) | 0.654 | 1.18 | (0.67–2.10) | 0.567 |
| Gender (male vs female) | 0.84 | (0.35–2.02) | 0.688 | 1.51 | (0.54–4.17) | 0.430 |
| Hematuria (vs no hematuria) | 2.94 | (0.39–22.01) | 0.293 | 1.25 | (0.15–10.32) | 0.833 |
| Proteinuria (g/24h) | 1.88 | (1.50–2.36) | <0.001* | 1.84 | (1.21–2.80) | 0.004* |
| Serum creatinine (per 10 μmoI/L) | 1.31 | (1.22–1.40) | <0.001* | 1.23 | (1.07–1.40) | 0.003* |
| Mean arterial pressure (per 10 mmHg) | 1.37 | (1.02–1.84) | 0.036* | 1.01 | (0.66–1.53) | 0.979 |
| M (M0 vs M1) | 0.79 | (0.32–1.90) | 0.591 | 0.75 | (0.26–2.13) | 0.585 |
| E (E0 vs E1) | 4.89 | (0.65–36.64) | 0.123 | 1.16 | (0.06–20.98) | 0.922 |
| S (S0 vs S1) | 1.92 | (0.56–6.57) | 0.298 | 1.26 | (0.26–6.22) | 0.775 |
| T (T0 vs T1+T2) | 6.84 | (3.46–13.53) | <0.001* | 4.00 | (1.81–8.86) | 0.001* |
| C (C0 vs C1+C2) | 1.74 | (0.75–4.06) | 0.198 | 0.94 | (0.32–2.77) | 0.904 |
| Tonsillectomy | 0.27 | (0.09–0.81) | 0.019* | 0.28 | (0.08–0.96) | 0.042* |
| Steroid/Immunosuppressant | 0.99 | (0.40–2.43) | 0.981 | 0.60 | (0.20–1.77) | 0.355 |
| RAS inhibitor | 0.80 | (0.31–2.10) | 0.655 | 0.87 | (0.24–3.09) | 0.825 |
Notes.
- HR
- hazard ratio
- CI
- confidence interval
*
Statistically significant.