Table 1. Screening of anti-Acanthamoeba activity and minimal inhibitory concentration (MIC) of semi-synthetic mangostin derivatives and chlorhexidine against A. triangularis WU19001 trophozoites and cysts.

Anti-Acanthamoeba agent	Anti-Acanthamoeba activity at a final concentration of 1 mg/mL		MIC (mg/mL)
	Trophozoite	Cyst	Trophozoite	Cyst
C1	+	+	0.128	0.064
C2	+	+	0.512	1.024
C3	+	+	0.512	1.024
Chlorhexidine	+	+	0.016	0.064

Note:

Symbol: +, positive with inhibition of more than 90% of viable growth compared with the control.