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. 2022 Dec 13;14(12):e32473. doi: 10.7759/cureus.32473

Table 2. History of COVID-19 vaccine uptake and menstrual disturbance among the participants (n=673).

*Not mutually exclusive (sum exceeded 100%).

    Frequency Percentage
Number of doses   Two 158 23.5
Three 515 76.5
First vaccine dose   Pfizer-BioNTech 510 75.8
Oxford-AstraZeneca 155 23.0
Moderna 8 1.2
Menstrual changes after the first dose No 364 54.1
Yes* 309 45.9
   Increase in menstrual cycle length    82 12.2
   Decrease in menstrual cycle length    94 14.0
   More pain    154 22.9
   Increase in amount    96 14.3
   Decrease in amount    29 4.3
   Intermenstrual bleeding    91 13.5
Duration between the first dose and the booster   Less than one month 109 16.2
1-2 months 158 23.5
≥3 months 406 60.3
Second vaccine dose   Pfizer-BioNTech 500 74.3
Oxford-AstraZeneca 147 21.8
Moderna 26 3.9
Menstrual changes after the second dose No 385 57.2
Yes* 288 42.8
   Increase in menstrual cycle length    79 11.7
   Decrease in menstrual cycle length    72 10.7
   More pain    144 21.4
   Increase in amount    81 12.0
   Decrease in amount    27 4.0
   Intermenstrual bleeding    84 12.5
Duration of changes in the cycles after COVID-19 vaccine (one dose or both doses) (n=303)   Less than one month 129 42.5
1-2 months 92 30.4
≥3 months 82 27.1