Table 3. Factors associated with post-COVID-19 vaccination menstrual changes among the participants.
* P<0.05. P-value was determined by the Chi-square test.
| Post-COVID-19 vaccination menstrual changes | p-value* | |||
| No n=314 N (%) | Yes n=359 N (%) | |||
| Age (years) | 18-22 (n=224) | 78 (34.8) | 146 (65.2) | <0.001* |
| 23-27 (n=283) | 160 (56.5) | 123 (43.5) | ||
| 28-32 (n=80) | 44 (55.0) | 36 (45.0) | ||
| 33-37 (n=34) | 14 (41.2) | 20 (58.8) | ||
| 38-45 (n=52) | 18 (34.6) | 34 (65.4) | ||
| Marital status | Single (n=505) | 240 (47.5) | 265 (52.5) | 0.660 |
| Married (n=154) | 67 (43.5) | 87 (56.5) | ||
| Divorced/widowed (n=14) | 7 (50.0) | 7 (50.0) | ||
| Residence | Al-Madinah (n=369) | 168 (45.5) | 201 (54.5) | 0.518 |
| Others (n=304) | 146 (48.0) | 158 (52.0) | ||
| Educational level | 6 (54.5) | 5 (45.5) | 0.021* | |
| High school/equivalent (n=168) | 62 (36.9) | 106 (63.1) | ||
| Bachelor's degree (n=456) | 224 (49.1) | 232 (50.9) | ||
| Postgraduate degree (n=38) | 22 (57.9) | 16 (42.1) | ||
| Number of COVID-19 vaccine doses | Two (n=158) | 61 (38.6) | 97 (61.4) | 0.020* |
| Three (n=515) | 253 (49.1) | 262 (50.9) | ||
| First vaccine dose | Pfizer-BioNTech (n=510) | 225 (44.1) | 285 (55.9) | 0.063 |
| Oxford-AstraZeneca (n=155) | 85 (54.8) | 70 (45.2) | ||
| Moderna (n=8) | 4 (50.0) | 4 (50.0) | ||
| Second vaccine dose | Pfizer-BioNTech (n=500) | 224 (44.8) | 276 (55.2) | 0.040* |
| Oxford-AstraZeneca (n=147) | 81 (55.1) | 66 (44.9) | ||
| Moderna (n=26) | 9 (34.6) | 17 (65.4) | ||
| Duration between the first dose and the booster | Less than one month (n=109) | 49 (45.0) | 60 (55.0) | 0.571 |
| 1-2 months (n=158) | 69 (43.7) | 89 (56.3) | ||
| ≥3 months (n=406) | 196 (48.3) | 210 (51.7) | ||