FIGURE 3.

EIF3B knockdown inhibited malignant melanoma tumor growth in vivo. A, A mice model was constructed via subcutaneous injection of shCtrl or shEIF3B A375 cells (n = 10/each group). B, The fluorescence intensity in shCtrl and shEIF3B groups was obtained through injecting D‐luciferase. C, The volume of tumors was checked from feeding to sacrifice. D, E, After sacrificing mice, the obtained tumors were weighed (D) and photographed (E). F, The value of Ki‐67 was detected by immunohistochemistry (IHC) analysis in tumor sections from mice. Magnification: 200×. Results are presented as mean ± SD. ***p < 0.001