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. 2022 Sep 15;113(12):4104–4119. doi: 10.1111/cas.15551

FIGURE 8.

FIGURE 8

Schematic overview of the potential roles of SAR1A in osteosarcoma metastasis. SAR1A promotes YAP activation through the RhoA/F‐actin pathway and promotes the transcription of downstream target genes to induce osteosarcoma metastasis. EMT, epithelial–mesenchymal transition; ER, endoplasmic reticulum