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. 2022 Dec 13;22:302. doi: 10.1186/s12866-022-02703-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Genetic correlation estimates for gut microbiota and longevity by LDSC regression analysis. a Circle color indicates the phenotype of longevity, whilethe red plot represents the healthspan, the green plot represents the parental lifespan,and the blue plot represents the parental longevity.Geneticcorrelation estimates with P<0.05 were annotated in the figure. All the genetic correlationsfor gut microbiota and longevity illustrated here can be found in Supplementary Table 2. b, c, d Circles represent the genetic correlation of healthspan, lifespan and longevity, respectively. The circle color indicates the degree of genetic correlation. The dark color has a high degree of genetic correlation, while the light color has a low degree of genetic correlation