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. Author manuscript; available in PMC: 2022 Dec 13.
Published in final edited form as: Genet Med. 2022 Sep 22;24(12):2526–2534. doi: 10.1016/j.gim.2022.08.023

Table 4.

Adjusted analysis for receiving genetic testing by different test types

Ancestry (N = 3648)
Health (N = 3648)
Cancer (N = 3648)
Characteristic Yes n (Wgt %a) No n (Wgt %a) Adjusted Odds Ratiob (95% CI) Yes n (Wgt %a) No n (Wgt %a) Adjusted Odds Ratiob (95% CI) Yes n (Wgt %a) No n (Wgt %a) Adjusted Odds Ratiob (95% CI)

Sex
 Male 221 (11) 1288 (89) Ref 76 (4) 1433 (96) Ref 32 (2) 1477 (98) Ref
 Female 317 (15) 1822 (85) 1.4 (1.0–2.1) 168 (7) 1971 (93) 2.1 (1.4–3.2) 113 (5) 2026 (95) 3.5 (1.9–6.2)
Age, y
 18–34 75 (12) 421 (88) Ref 50 (6) 446 (94) Ref 10 (1) 486 (99) Ref
 35–49 87 (11) 619 (89) 0.8 (0.5–1.4) 58 (6) 648 (94) 0.7 (0.4–1.5) 33 (4) 673 (96) 3.0 (1.0–9.4)
 50–64 162 (15) 965 (85) 1.1 (0.7–1.9) 70 (6) 1057 (94) 0.8 (0.4–1.4) 55 (6) 1072 (94) 3.2 (0.9–10.9)
 65–74 135 (15) 689 (85) 1.3 (0.7–2.3) 43 (5) 781 (95) 0.8 (0.3–2.0) 31 (3) 793 (97) 1.4 (0.3–6.6)
 >75 79 (14) 416 (87) 1.5 (0.8–3.0) 23 (4) 472 (96) 0.7 (0.2–2.5) 16 (3) 479 (97) 1.4 (0.2–8.7)
Race/ethnicity
 Non-Hispanic White 387 (18) 1810 (82) Ref 171 (8) 2026 (92) Ref 95 (4) 2102 (96) Ref
 Non-Hispanic Black 52 (10) 495 (90) 0.5 (0.3–0.9) 24 (4) 523 (96) 0.9 (0.4–2.0) 21 (4) 526 (96) 1.2 (0.6–2.6)
 Non-Hispanic Asian 17 (10) 156 (90) 0.7 (0.3–1.8) 12 (7) 161 (93) 1.5 (0.5–4.6) 2 (1) 171 (99) 0.2 (0.01–3.1)
 Non-Hispanic Otherc 26 (19) 110 (81) 1.5 (0.6–3.5) 16 (12) 120 (88) 1.6 (0.6–3.9) 9 (7) 127 (93) 3.2 (0.4–23.6)
 Hispanic 56 (9) 539 (91) 0.4 (0.3–0.7) 21 (5) 574 (96) 0.3 (0.1–0.9) 18 (3) 577 (97) 0.5 (0.2–1.0)
Level of education
 High school or less 73 (7) 855 (93) Ref 40 (4) 888 (96) Ref 35 (4) 893 (96) Ref
 Some college 465 (15) 2255 (85) 1.9 (1.2–2.9) 204 (7) 2516 (93) 1.3 (0.6–2.9) 110 (4) 2610 (96) 0.7 (0.5–1.7)
Employment statusd
 Employed 267 (14) 1552 (86) Ref 142 (7) 1677 (93) Ref 77 (4) 1742 (96) Ref
 Not employed 261 (12) 1454 (88) 0.9 (0.6–1.3) 95 (4) 1620 (96) 0.6 (0.4–1.0) 66 (4) 1649 (96) 1.1 (0.5–2.2)
Incomee
 Less than $20,000 37 (6) 546 (94) Ref 30 (3) 553 (97) Ref 20 (3) 563 (97) Ref
 $20,000-$49,999 106 (11) 747 (89) 1.7 (0.8–3.5) 47 (5) 806 (95) 1.6 (0.6–4.2) 28 (2) 825 (98) 0.7 (0.3–2.0)
 $50,000-$99,999 175 (16) 784 (84) 2.4 (1.2–5.0) 59 (5) 900 (95) 1.4 (0.6–3.1) 39 (4) 920 (96) 2.0 (0.8–5.0)
 $100,000 or higher 178 (15) 719 (85) 2.0 (0.9–4.3) 96 (8) 801 (92) 2.0 (1.0–4.1) 47 (5) 850 (95) 2.2 (1.0–4.9)
Marital status
 Married 319 (15) 1634 (85) Ref 143 (7) 1810 (93) Ref 75 (4) 1878 (96) Ref
 Otherf 138 (13) 920 (87) 0.9 (0.6–1.4) 69 (6) 989 (94) 1.1 (0.7–1.9) 52 (5) 1006 (95) 1.3 (0.6–2.7)
 Never married 81 (10) 556 (90) 0.8 (0.5–1.3) 32 (4) 605 (96) 0.6 (0.3–1.3) 18 (2) 619 (98) 0.8 (0.3–2.5)
Personal history of cancer
 No 476 (13) 2724 (87) Ref 217 (6) 2983 (94) Ref 98 (3) 3102 (97) Ref
 Yes 62 (11) 386 (89) 0.8 (0.4–1.4) 27 (6) 421 (94) 1.2 (0.6–2.1) 47 (14) 401 (86) 5.3 (2.7–10.3)
Family history of cancere
 No 83 (9) 621 (91) Ref 36 (6) 668 (94) Ref 9 (1) 695 (99) Ref
 Yes 407 (15) 2142 (85) 1.5 (1.0–2.2) 186 (6) 2363 (94) 0.9 (0.4–1.8) 125 (5) 2424 (95) 2.5 (0.8–8.3)
 Not Sure 38 (11) 258 (89) 1.8 (0.8–3.9) 16 (5) 280 (95) 1.2 (0.3–4.5) 7 (1) 289 (99) 0.7 (0.1–4.1)

Ref, reference group; Wgt, weighted.

a

These were calculated using jackknife replication.

b

Odds ratios were adjusted for the other characteristics shown in this table.

c

Those identifying as Alaska Native/American Indian, Pacific Islander, or of multiple races were combined into an “other” race category owing to low cell counts.

d

Participants who reported of being employed full or part time were categorized as “employed.” Participants who were retired, disabled, students, homemakers, or other were categorized as “not employed.” n = 121 participants were missing responses for employment.

e

n =377 participants were missing for income, and 109 were missing responses for family history of cancer.

f

The “other” category included participants who were widowed, divorced, or separated.