FIGURE 6.

Schematic drawings of (A) the hierarchical quaternary structure of rpM179 from monomer to dimer to six-dimer oligomer ring to nanosphere as suggested by the literature (Bromley et al., 2011; Fang et al., 2011) and from oligomer ring to nanosphere for H3 and H8 as suggested by the adsorption and DLS results of this study. Smaller oligomers are shown for H3 and H8 as indicated by the AFM and TEM results. (B) Differences in adsorption onto HAP resulting in higher adsorption amounts for H8, and lower adsorption amounts for H3 compared to rpM179. The oligomer rings are oriented perpendicular to the surface for clarity in the schematic and because that orientation would promote interactions with the C-terminus. The orientation of rings onto the HAP surface is not known at the present time, however.