Fig 1.

Features of cohorts of patients with IEI and SARS-CoV-2 infection. (A) Age of patients with the indicated IEI. Data are shown as median ages and quartiles for each patient group. Values above each data set represent the mean ages of patients with the indicated IEI. (B) CFR for all IEI patients, as well as range for the CFR in the general population (www.covid19.who.int/, www.worldometers.info/coronavirus/). Values in each patient group represent the number of deaths/total number of patients with the indicated IEI. Agamma, Agammaglobulinemia; AIRE, patients with APECED; ATM, ataxia telangiectasia; C’ def, complement deficiency; CGD, chronic granulomatous disease; FMF, familial Mediterranean fever; IFNAR1/2, patients with pathogenic variants in type I IFN receptors; IRF7, MYD88/IRAK4, patients with pathogenic variants in IRF7 or MYD88/IRAK4 that disrupt type I IFN signaling.