(A) Percent of original BW was collected during clinical exams on 1 and 3 dpi. Mink lost a significant amount of BW at both 1 and 3 dpi (1-way ANOVA with Tukey’s multiple comparisons test). (B) Mink were assessed at least twice daily and evaluated for hunched posture, respiratory effort, mentation, nasal discharge, and appetite. (C) CBC values collected after infection. The medians with the 95% CI are depicted. (D) Increased neutrophil/lymphocyte ratio as determined from the CBC. Mean with SD depicted, 2-way ANOVA with Tukey’s multiple comparisons test. (E) Selected blood chemistry values, median with 95% CI depicted.