Table 2. Multivariable model for the association of cigarette smoking with diminished ovarian reserve (DOR).
| All womena | Women without PCOSb | |||
|---|---|---|---|---|
| N | OR (95% CI) for DOR | N | OR (95% CI) for DOR | |
| Current smoking status, using cotinine measurement | ||||
| Nonsmoker | 71 | Referent | 47 | Referent |
| Passive smoker | 70 | 1.32 (0.59–3.0) | 38 | 0.85 (0.33–2.19) |
| Active smoker | 58 | 0.62 (0.24–1.56) | 36 | 0.52 (0.18–1.52) |
| Self-reported cigarettes/day | ||||
| Treated continuously | 207 | 1.05 (0.997–1.11) | 125 | 1.08 (1.01–1.15)c |
| Categories: | ||||
| None | 174 | Referent | 107 | Referent |
| 1–9 | 15 | 0.27 (0.03–2.27) | 8 | 0.44 (0.05–4.27) |
| ≥10 | 18 | 2.64 (0.81–8.64) | 10 | 4.58 (0.91–23.02) |
| Self-reported cumulative lifetime exposure in pack-years | ||||
| Treated continuously | 207 | 1.05 (0.97–1.13) | 125 | 1.08 (0.99–1.18) |
| Categories: | ||||
| Never | 150 | Referent | 93 | Referent |
| 1–5 | 35 | 0.67 (0.24–1.82) | 21 | 1.09 (0.36–3.34) |
| >5 | 22 | 1.48 (0.49–4.47) | 11 | 2.51 (0.61–10.23) |
a Models adjusted for age and polycystic ovary syndrome
b Models adjusted for age
c P-value = 0.04